Vaccines are available to protect older adults from severe RSV. Vaccines for pregnant women or monoclonal antibody products are available to protect infants and young children from severe RSV. Vaccines are available to protect older adults from severe RSV. Vaccines for pregnant women or monoclonal antibody products are available to protect infants and young children from severe RSV. Nirsevimab is an injectable monoclonal antibody that prevents severe RSV disease in infants and young children. Monoclonal antibodies do not activate the immune system, as would occur with infection or vaccination (active immunization). Rather, the antibodies themselves protect against disease (i.e., passive immunization). Because nirsevimab does not activate the immune system, protection is likely most effective the weeks after nirsevimab is given and wanes over time. Nirsevimab does not provide long-term immunity to RSV disease but provides protection to infants when they are most at risk of getting severe RSV disease. As children get older, they are less likely to get severe symptoms from RSV infection.
The Advisory Committee on Immunization Practices (ACIP) recommends adults 50–59 years of age who are at increased risk of severe RSV disease receive a single dose of RSV vaccine. At this time, RSV vaccination is recommended as a single dose only. Persons who have already received RSV vaccination are not recommended to receive another dose. RSV vaccine can be administered with any product licensed in this age group. As of March 27, 2025, that includes GSK's Arexvy and Pfizer's Abrysvo. There is no preferential recommendation for any licensed product over another.
There are steps that can be taken to help prevent the spread of RSV. Covering coughs and sneezes, practicing frequent hand washing, refraining from kissing other people, and disinfecting surfaces may help stop the spread of RSV. Persons with RSV illness should not share cups or eating utensils with others, and persons with cold-like symptoms should not interact with high-risk children. When possible, limiting the time that high-risk children spend in child-care centers or other potentially contagious settings may help prevent infection and spread of the virus during the RSV season.
A drug called palivizumab is available to prevent severe RSV illness in certain infants and children who are at high risk. The drug can help prevent development of serious RSV disease, but it cannot prevent infection with RSV or help cure or treat children already suffering from serious RSV disease.