TPPA

Syphilis Confirmation Particle Agglutination (TP-PA) 

Laboratory Fee Schedule

Procedure: MCS0318A

CPT: 86780


Syphilis Confirmation Particle Agglutination (TP-PA)
Synonym(s): Syphilis Confirmation Particle Agglutination (TP-PA)
Requisition Form G-2A
Test Description Qualitative gelatin particle agglutination assay for the detection of T. pallidum antibodies in serum or plasma
Pre-Approval Needed N/A
Supplemental Information Required N/A
Supplemental Form(s) N/A
Performed on Specimens from (sources) Human
Sample/Specimen Type for Testing Serum
Minimum Volume/Size Required 100 µL
Storage/Preservation Prior to Shipping
  • Store at 2° to 8°C for 5 days.
  • For long term storage, remove serum and store frozen at -20°C or colder.
Transport Medium N/A
Specimen Labeling
  • Two patient-specific identifiers required (e.g., patient full name, date of birth, Medical record number)
  • Identifiers on specimen must exactly match submission form.
Shipping and Specimen Handling Requirements
  • Ship according to Dangerous Goods Regulations, IATA, and/or CFR 49.
  • Handle as infectious agent using universal precautions.
  • Triple contain in accordance with federal shipping regulations for infectious agents.
    Additional forms & resources
Method Qualitative agglutination assay
Turn-around Time 3-5 days
Interferences/Limitations Yaws, Pinta
Common Causes for Rejection
  • insufficient quantity
  • unacceptable specimen type or source
  • improper shipping conditions
  • expired media or collection container
  • discrepancies between specimen label and submission form, and/or incomplete or missing submission form.
Additional Information Specimens giving inconclusive results should be retested.  A repeated inconclusive specimen should be reported as inconclusive for follow-up and another specimen drawn in two weeks and/or confirmed by other methods.

Last updated April 15, 2021