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Carbapenum-Resistant Enterobacteriaceae

New Protocol Offers Hospitals Option to Detect Bacterial Contamination of Duodenoscopes

Combating antibiotic-resistant infections and protecting patients are national priorities. Recent outbreaks of CRE (carbapenem-resistant Enterobacteriaceae) related to a type of endoscope called a duodenoscope have occurred without identified lapses of infection control. Distal end, Model TJF-Q180V (Olympus) – Illustrating the orientation of forceps elevator in the (a) ‘lowered/ closed’ position and (b) ‘raised/ opene

With input from healthcare facilities, professional partners and stakeholders, CDC has developed an interim protocol for facilities that want to test their duodenoscopes for contamination with bacteria, including CRE, after the cleaning and disinfection process. 

These interim protocols provide a step-by-step approach for facilities wanting to check whether scopes could be a source of infection for patients. Included are suggestions for how scopes should be sampled, options for the frequency and types of sampling, how to test those samples in a lab, and how to interpret results. Sampling is not a substitute for correct cleaning and disinfection (“reprocessing”) of these scopes.  The interim protocols are intended to supplement and not replace manufacturer- recommended reprocessing procedures.

PDF for Download

Interim Duodenoscope Surveillance Protocol

Interim Duodenoscope Sampling Method

Interim Duodenoscope Culture Method

CDC Infographic

Risk of CRE Infection

View the CDC’s Carbapenem-resistant Enterobacteriaceae (CRE) webpage to learn more about this condition.

2012 CRE Toolkit - Guidance for Control of Carbapenem-resistant Enterobacteriaceae (CRE)  (PDF, 2.98 MB)

Last updated March 2, 2021